{"id":5720,"date":"2017-01-31T16:42:48","date_gmt":"2017-02-01T00:42:48","guid":{"rendered":"https:\/\/www.washington.edu\/research\/?page_id=5720"},"modified":"2026-01-30T10:13:04","modified_gmt":"2026-01-30T18:13:04","slug":"renew","status":"publish","type":"page","link":"https:\/\/www.washington.edu\/research\/hsd\/study-activities\/renew\/","title":{"rendered":"Renew Your IRB Approval"},"content":{"rendered":"<p><img decoding=\"async\" class=\"WP-PrintIcon\" src=\"https:\/\/www.washington.edu\/research\/wp-content\/plugins\/wp-print\/images\/printer_famfamfam.gif\"  alt=\"Print\" title=\"Print\" style=\"border: 2px;\">&nbsp;<a href=\"https:\/\/www.washington.edu\/research\/hsd\/study-activities\/renew\/print\/\" title=\"Print\" rel=\"nofollow\" target=\"_blank\">Print<\/a><\/p>\n<div class=\"table-of-contents\">\n<h2 id=\"toc\">Table of Contents<\/h2>\n<ul class=\"list-unstyled\">\n<li><a href=\"#1\">Before You Begin<\/a>\n<ul>\n<li><a href=\"#1a\">Does your study require continuing review?<\/a><\/li>\n<li><a href=\"#1b\">How early should you apply for continuing review?<\/a><\/li>\n<li><a href=\"#1c\">What happens if IRB approval expires?<\/a><\/li>\n<\/ul>\n<\/li>\n<li><a href=\"#2\">Steps to Renew Your IRB Approval<\/a><\/li>\n<li><a href=\"#3\">What to Expect After Submitting<\/a><\/li>\n<\/ul>\n<\/div>\n<h2 id=\"1\">Before You Begin<\/h2>\n<div class=\"accordion \" id=\"accordion\">\n<div class=\"screen-reader-text\"><\/div>\n<div class=\"card\" id=\"1a\">\n<div class=\"card-header\" id=\"accordion-header\">\n<h3 class=\"mb-0\"><button class=\"btn btn-link\" type=\"button\" data-toggle=\"collapse\" data-target=\"#collapse\" aria-expanded=\"false\" aria-controls=\"collapse\"><span class=\"btn-text\">Does your study require continuing review?<\/span><span class=\"arrow-box\"><span class=\"arrow\"><\/span><\/span><\/button><\/h3>\n<\/div>\n<div id=\"collapse\" class=\"collapse \" aria-labelledby=\"collapse\" data-parent=\"#accordion\" role=\"region\">\n<table>\n<tbody>\n<tr>\n<th>Review Type<\/th>\n<th class=\"views\">Continuing Review Requirements<\/th>\n<\/tr>\n<tr class=\"odd\">\n<td>Determinations (Exempt, Not Human Subjects Research, Not Research,  91探花Not Engaged)<\/td>\n<td>Continuing review <strong>not<\/strong> required. Do not submit a request to renew.<\/td>\n<\/tr>\n<tr class=\"even\">\n<td>External (Non-UW) IRB Review<\/td>\n<td>Apply for continuing review with the reviewing IRB if required for the study. You do not need to submit documentation of renewed IRB approval to HSD. Review the <a href=\"https:\/\/www.washington.edu\/research\/forms-and-templates\/checklist-external-irb-uw-researchers\/\">External IRB Checklist for  91探花Researchers<\/a> for more information.<\/td>\n<\/tr>\n<tr class=\"odd\">\n<td>\u00a0 91探花IRB Approved Studies<\/td>\n<td>Not all studies that receive  91探花IRB approval require continuing review. If your study requires continuing review:<\/p>\n<ul>\n<li>An expiration date will be listed in your IRB approval letter and in the study workspace in Zipline<\/li>\n<li>The PI, any PI proxies, and the primary contact for the study will receive automatic email reminders 60 days and 30 days before approval expires<\/li>\n<\/ul>\n<p>If you have completed all recruitment, study procedures, and analysis of identifiable data, you should <a href=\"https:\/\/www.washington.edu\/research\/hsd\/study-activities\/close\/\">close your IRB application<\/a> instead.<\/td>\n<\/tr>\n<tr class=\"even\">\n<td>Multi-institutional  91探花IRB Approved Studies<\/td>\n<td>Continuing review is conducted at the study level. Any information about other institutions relying on the  91探花for review should be reported with the overall study continuing review. Review <a href=\"https:\/\/www.washington.edu\/research\/hsd\/training\/zipline-online-help-library\/managing-multi-site-studies\/#CR\">Multi-site Continuing Review and Closure<\/a> for detailed steps.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<\/div>\n<div class=\"card\" id=\"1b\">\n<div class=\"card-header\" id=\"accordion-header\">\n<h3 class=\"mb-0\"><button class=\"btn btn-link\" type=\"button\" data-toggle=\"collapse\" data-target=\"#collapse\" aria-expanded=\"false\" aria-controls=\"collapse\"><span class=\"btn-text\">How early should you apply for continuing review?<\/span><span class=\"arrow-box\"><span class=\"arrow\"><\/span><\/span><\/button><\/h3>\n<\/div>\n<div id=\"collapse\" class=\"collapse \" aria-labelledby=\"collapse\" data-parent=\"#accordion\" role=\"region\">\n<p>Many applications for IRB renewal must be reviewed by the convened IRB instead of by an expedited reviewer, so make sure to give the IRB plenty of time to review your application! <strong>We recommend submitting your continuing review application at least 45 days before approval expires to avoid a lapse in approval.<\/strong><\/p>\n<\/div>\n<\/div>\n<div class=\"card\" id=\"1c\">\n<div class=\"card-header\" id=\"accordion-header\">\n<h3 class=\"mb-0\"><button class=\"btn btn-link\" type=\"button\" data-toggle=\"collapse\" data-target=\"#collapse\" aria-expanded=\"false\" aria-controls=\"collapse\"><span class=\"btn-text\">What happens if IRB approval expires?<\/span><span class=\"arrow-box\"><span class=\"arrow\"><\/span><\/span><\/button><\/h3>\n<\/div>\n<div id=\"collapse\" class=\"collapse \" aria-labelledby=\"collapse\" data-parent=\"#accordion\" role=\"region\">\n<p><strong>All human subjects research activities must stop.<\/strong> This includes recruitment, advertisement, screening, enrollment, consent, interventions, interactions, and collection or analysis of private identifiable information. Also, funding related to those activities or that was released because of a DOHR determination cannot be spent.<\/p>\n<p><strong>Exceptions:<\/strong> If any of the following exceptions apply, immediately <a href=\"https:\/\/www.washington.edu\/research\/hsd\/study-activities\/report-events-and-new-information\/\">report this to the  91探花IRB<\/a> including information about the continued research activities and the rationale for continuing them:<\/p>\n<ul>\n<li>Continuation of activities necessary to eliminate apparent, immediate hazards to subjects.<\/li>\n<li>The research intervention (if any) may be of direct benefit to individual subjects.<\/li>\n<li>Withholding the research intervention (if any) may increase risks to subjects.<\/li>\n<\/ul>\n<p>Submit a renewal or close your application as soon as possible. If a renewal or closure is not received and IRB approval has been lapsed for 90 days HSD may administratively close the study.<\/p>\n<p>In some circumstances, HSD may refuse to review additional submissions from the researcher until a status report is received and approved or the application closed. Lapsed IRB approval may be considered continuing noncompliance, and the study may be \u201cterminated\u201d by the IRB.<\/p>\n<p>Review section 5.4 of <a href=\"https:\/\/www.washington.edu\/research\/policies\/sop-irb-review-2\/\">SOP IRB Review<\/a> for more information.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<h2 id=\"2\">Steps to Renew Your IRB Approval<\/h2>\n<div class=\"accordion \" id=\"accordion\">\n<div class=\"screen-reader-text\"><\/div>\n<div class=\"card\">\n<div class=\"card-header\" id=\"accordion-header\">\n<h3 class=\"mb-0\"><button class=\"btn btn-link\" type=\"button\" data-toggle=\"collapse\" data-target=\"#collapse\" aria-expanded=\"false\" aria-controls=\"collapse\"><span class=\"btn-text\">Step 1: Complete the Status Report Form<\/span><span class=\"arrow-box\"><span class=\"arrow\"><\/span><\/span><\/button><\/h3>\n<\/div>\n<div id=\"collapse\" class=\"collapse \" aria-labelledby=\"collapse\" data-parent=\"#accordion\" role=\"region\">\n<p><strong>To request renewal of IRB approval,<\/strong> complete the <a href=\"https:\/\/www.washington.edu\/research\/forms-and-templates\/application-status-report-renew-or-close\/\">Status Report form<\/a>.<\/p>\n<p><strong>To request renewal of a Delayed Onset Human Research (DOHR) determination<\/strong>, complete the <a href=\"https:\/\/www.washington.edu\/research\/forms-and-templates\/application-determination-delayed-onset-human-research\/\">APPLICATION Determination, Delayed Onset Human Research<\/a> and follow the instructions on the form.<\/p>\n<\/div>\n<\/div>\n<div class=\"card\">\n<div class=\"card-header\" id=\"accordion-header\">\n<h3 class=\"mb-0\"><button class=\"btn btn-link\" type=\"button\" data-toggle=\"collapse\" data-target=\"#collapse\" aria-expanded=\"false\" aria-controls=\"collapse\"><span class=\"btn-text\">Step 2: Prepare Any Supporting Documents for Upload (If Needed)<\/span><span class=\"arrow-box\"><span class=\"arrow\"><\/span><\/span><\/button><\/h3>\n<\/div>\n<div id=\"collapse\" class=\"collapse \" aria-labelledby=\"collapse\" data-parent=\"#accordion\" role=\"region\">\n<p><strong>Most continuing review applications only require the status report form<\/strong>, but you have the option to upload other documents related to the continuing review such as sponsor progress reports or radiation safety renewals.<\/p>\n<p><strong>Any\u00a0 Data and Safety Monitoring Board (DSMB) reports should be submitted separately using the <a href=\"https:\/\/www.washington.edu\/research\/hsd\/study-activities\/report-events-and-new-information\/\">reporting process<\/a>. <\/strong><\/p>\n<\/div>\n<\/div>\n<div class=\"card\">\n<div class=\"card-header\" id=\"accordion-header\">\n<h3 class=\"mb-0\"><button class=\"btn btn-link\" type=\"button\" data-toggle=\"collapse\" data-target=\"#collapse\" aria-expanded=\"false\" aria-controls=\"collapse\"><span class=\"btn-text\">Step 3: Complete the Continuing Review in Zipline<\/span><span class=\"arrow-box\"><span class=\"arrow\"><\/span><\/span><\/button><\/h3>\n<\/div>\n<div id=\"collapse\" class=\"collapse \" aria-labelledby=\"collapse\" data-parent=\"#accordion\" role=\"region\">\n<ul>\n<li>Navigate to the study you need to renew and click Renew or Close under Next Steps<\/li>\n<\/ul>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-31128 size-full\" src=\"https:\/\/www.washington.edu\/research\/wp-content\/uploads\/2019\/12\/Continuing-Review-and-Closure-Homepage-Renew-or-Close.png\" alt=\"screenshot of the renew or close button for a zipline study\" width=\"729\" height=\"596\" srcset=\"https:\/\/www.washington.edu\/research\/wp-content\/uploads\/2019\/12\/Continuing-Review-and-Closure-Homepage-Renew-or-Close.png 729w, https:\/\/www.washington.edu\/research\/wp-content\/uploads\/2019\/12\/Continuing-Review-and-Closure-Homepage-Renew-or-Close-300x245.png 300w, https:\/\/www.washington.edu\/research\/wp-content\/uploads\/2019\/12\/Continuing-Review-and-Closure-Homepage-Renew-or-Close-375x307.png 375w\" sizes=\"auto, (max-width: 729px) 100vw, 729px\" \/><\/p>\n<ul>\n<li>Complete the forms and upload the status report form and any supporting documents<\/li>\n<\/ul>\n<p><strong>Common Mistakes:<\/strong><\/p>\n<ul>\n<li><strong>Missing explanations for items or events from the past year. <\/strong>Make sure that you accurately checked all applicable items and provided a summary explanation for each item you did not check.<\/li>\n<li><strong>Checking the incorrect research milestones<\/strong>. Many researchers believe that IRB approval must be renewed if any identifiable private information or specimens will be retained. However, the IRB application may be closed if the data analysis described in the IRB application has been completed and if retention of the identifiable data is consistent with information in the IRB application.<\/li>\n<li><strong><strong>Not accurately reporting subject numbers for multi-site studies. <\/strong><\/strong>Make sure to distinguish between the number of subjects for the UW\u2019s site versus the number of subjects across the entire multi-site study.<\/li>\n<\/ul>\n<p>For step by step instructions:<\/p>\n<ul>\n<li><a href=\"https:\/\/www.washington.edu\/research\/hsd\/training\/zipline-online-help-library\/continuing-review-and-closure\/\">Submit Continuing Review or Closure<\/a><\/li>\n<\/ul>\n<\/div>\n<\/div>\n<div class=\"card\">\n<div class=\"card-header\" id=\"accordion-header\">\n<h3 class=\"mb-0\"><button class=\"btn btn-link\" type=\"button\" data-toggle=\"collapse\" data-target=\"#collapse\" aria-expanded=\"false\" aria-controls=\"collapse\"><span class=\"btn-text\">Step 4: The PI or a PI Proxy must submit<\/span><span class=\"arrow-box\"><span class=\"arrow\"><\/span><\/span><\/button><\/h3>\n<\/div>\n<div id=\"collapse\" class=\"collapse \" aria-labelledby=\"collapse\" data-parent=\"#accordion\" role=\"region\">\n<p>The Submit activity must be <strong>completed by the PI or a PI proxy<\/strong> once the continuing review is ready to go to HSD.<\/p>\n<ul>\n<li>Select <strong>Submit<\/strong> in the continuing review workspace and provide required verifications<\/li>\n<\/ul>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-31031 aligncenter\" src=\"https:\/\/www.washington.edu\/research\/wp-content\/uploads\/Managing-Multi-site-Studies-submit-CR.png\" alt=\"screenshot of the submit button\" width=\"262\" height=\"280\" \/><\/p>\n<\/div>\n<\/div>\n<\/div>\n<h2 id=\"3\">What to Expect After Submitting<\/h2>\n<p>The continuing review transitions to Pre-Review state and is now in HSD\u2019s queue for review.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-31126 size-large\" src=\"https:\/\/www.washington.edu\/research\/wp-content\/uploads\/Continuing-Review-and-Closure-CR-in-pre-review.png\" alt=\"screenshot of a continuing review in Pre-Review state\" width=\"1024\" height=\"337\" \/><\/p>\n<p>After the IRB has reviewed the application, the PI, any PI proxies, and primary contact will receive a notification that:<\/p>\n<ul>\n<li>The IRB has approved the renewal; OR<\/li>\n<li>The IRB requires more information or a change before approving the renewal<\/li>\n<\/ul>\n<p>Visit <a href=\"https:\/\/www.washington.edu\/research\/hsd\/training\/zipline-online-help-library\/respond-to-hsd\/\">Respond to HSD<\/a> for more information on submitting responses.<\/p>\n<p><strong>After Continuing Review Approval<\/strong><\/p>\n<p>After the continuing review is approved, the parent study will be updated. The new expiration date is published to the parent study. The PI, PI proxy, and primary contact also receive a notification containing the Continuing Review approval letter.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Table of Contents Before You Begin Does your study require continuing review? How early should you apply for continuing review? What happens if IRB approval expires?&#8230;<\/p>\n","protected":false},"author":15,"featured_media":0,"parent":11143,"menu_order":3,"comment_status":"closed","ping_status":"closed","template":"templates\/page-builder-units-small-hero.php","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-5720","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.1.1 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Renew Your IRB Approval -  91探花Research<\/title>\n<meta name=\"description\" content=\"Overview of how to complete continuing review of an ongoing study.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.washington.edu\/research\/hsd\/study-activities\/renew\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Renew Your IRB Approval - 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