{"id":5777,"date":"2017-01-20T15:29:29","date_gmt":"2017-01-20T23:29:29","guid":{"rendered":"https:\/\/www.washington.edu\/research\/?page_id=5777"},"modified":"2026-01-30T10:17:33","modified_gmt":"2026-01-30T18:17:33","slug":"close","status":"publish","type":"page","link":"https:\/\/www.washington.edu\/research\/hsd\/study-activities\/close\/","title":{"rendered":"Close Your IRB Application"},"content":{"rendered":"<p><img decoding=\"async\" class=\"WP-PrintIcon\" src=\"https:\/\/www.washington.edu\/research\/wp-content\/plugins\/wp-print\/images\/printer_famfamfam.gif\"  alt=\"Print\" title=\"Print\" style=\"border: 2px;\">&nbsp;<a href=\"https:\/\/www.washington.edu\/research\/hsd\/study-activities\/close\/print\/\" title=\"Print\" rel=\"nofollow\" target=\"_blank\">Print<\/a><\/p>\n<div class=\"table-of-contents\">\n<h2 id=\"toc\">Table of Contents<\/h2>\n<ul class=\"list-unstyled\">\n<li><a href=\"#1\">Before You Begin<\/a>\n<ul>\n<li><a href=\"#1a\">Are you required to close your application?<\/a><\/li>\n<li><a href=\"#1b\">Does your study meet the criteria for closure?<\/a><\/li>\n<li><a href=\"#1c\">Common Concerns<\/a><\/li>\n<\/ul>\n<\/li>\n<li><a href=\"#2\">Steps to Close Your IRB Approval<\/a><\/li>\n<li><a href=\"#3\">What to Expect After Submitting<\/a><\/li>\n<\/ul>\n<\/div>\n<h2 id=\"1\">Before You Begin<\/h2>\n<div class=\"accordion \" id=\"accordion\">\n<div class=\"screen-reader-text\"><\/div>\n<div class=\"card\" id=\"1a\">\n<div class=\"card-header\" id=\"accordion-header\">\n<h3 class=\"mb-0\"><button class=\"btn btn-link\" type=\"button\" data-toggle=\"collapse\" data-target=\"#collapse\" aria-expanded=\"false\" aria-controls=\"collapse\"><span class=\"btn-text\">Are you required to close your application?<\/span><span class=\"arrow-box\"><span class=\"arrow\"><\/span><\/span><\/button><\/h3>\n<\/div>\n<div id=\"collapse\" class=\"collapse \" aria-labelledby=\"collapse\" data-parent=\"#accordion\" role=\"region\">\n<table>\n<tbody>\n<tr>\n<th>Review Type<\/th>\n<th class=\"views\">Continuing Review Requirements<\/th>\n<\/tr>\n<tr class=\"odd\">\n<td>\u00a0 91探花IRB Approved Studies<\/td>\n<td>Application should be closed if the criteria for closure listed below are met.<\/td>\n<\/tr>\n<tr class=\"even\">\n<td>Multi-institutional  91探花IRB Approved Studies<\/p>\n<p>&nbsp;<\/td>\n<td>If the involvement of a relying institution has ended, <a href=\"https:\/\/www.washington.edu\/research\/hsd\/training\/zipline-online-help-library\/managing-multi-site-studies\/#site%20closure\">submit a site closure<\/a> to the IRB. This closes the SITE record while leaving the parent STUDY record open.<\/p>\n<p>To close the study once the closure criteria listed below have been met, follow the <a href=\"https:\/\/www.washington.edu\/research\/hsd\/training\/zipline-online-help-library\/managing-multi-site-studies\/#CR\">Multi-site Continuing Review or Closure instructions<\/a>.<\/td>\n<\/tr>\n<tr class=\"odd\">\n<td>External (Non-UW) IRB Review<\/td>\n<td>Contact <a href=\"mailto:hsdrely@uw.edu\">hsdrely@uw.edu<\/a> to initiate the study closure process.<\/td>\n<\/tr>\n<tr class=\"even\">\n<td>Exempt Determinations<\/td>\n<td>Closure is <strong>not<\/strong> required. If your research is completed and you wish to stop receiving automated email notices, email <a href=\"mailto:hsdinfo@uw.edu\">hsdinfo@uw.edu<\/a> to request that your exempt study be administratively closed.<\/td>\n<\/tr>\n<tr class=\"odd\">\n<td>Not Human Subjects Research, Not Research,  91探花Not Engaged Determinations<\/td>\n<td>Applications with these determinations are considered completed and cannot be closed.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<\/div>\n<div class=\"card\" id=\"1b\">\n<div class=\"card-header\" id=\"accordion-header\">\n<h3 class=\"mb-0\"><button class=\"btn btn-link\" type=\"button\" data-toggle=\"collapse\" data-target=\"#collapse\" aria-expanded=\"false\" aria-controls=\"collapse\"><span class=\"btn-text\">Does your study meet the criteria for closure?<\/span><span class=\"arrow-box\"><span class=\"arrow\"><\/span><\/span><\/button><\/h3>\n<\/div>\n<div id=\"collapse\" class=\"collapse \" aria-labelledby=\"collapse\" data-parent=\"#accordion\" role=\"region\">\n<p>Criteria:<\/p>\n<ul>\n<li>All subjects have completed all study-related interventions and procedures, including any follow-up.<\/li>\n<li>You have obtained all private identifiable data and\/or specimens from all subjects.<\/li>\n<li>You have completed your analysis of all private identifiable data and specimens, as described in your IRB application.<\/li>\n<\/ul>\n<p><strong>OR<\/strong><\/p>\n<ul>\n<li>The study was never open for enrollment, no subjects were ever enrolled.<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<div class=\"card\" id=\"1c\">\n<div class=\"card-header\" id=\"accordion-header\">\n<h3 class=\"mb-0\"><button class=\"btn btn-link\" type=\"button\" data-toggle=\"collapse\" data-target=\"#collapse\" aria-expanded=\"false\" aria-controls=\"collapse\"><span class=\"btn-text\">Common Concerns<\/span><span class=\"arrow-box\"><span class=\"arrow\"><\/span><\/span><\/button><\/h3>\n<\/div>\n<div id=\"collapse\" class=\"collapse \" aria-labelledby=\"collapse\" data-parent=\"#accordion\" role=\"region\">\n<p><strong>Identifiers do not need to be destroyed in order to close an IRB application.<\/strong> IRB approval does not have to be maintained during the records retention period if the study procedures and analyses described in the IRB application have been completed.<\/p>\n<p><strong>You can still provide information to subjects about study results or other studies if the activities were approved as part of the application.<\/strong> When former subjects are provided with information about other studies, the IRB review of those other studies must include review and approval of the information and recruiting efforts.<\/p>\n<p><strong>The  91探花IRB application can be closed if the study is permanently closed to enrollment at all sites under the  91探花IRB\u2019s review, all subjects under the  91探花IRB\u2019s oversight have completed all research-related interventions and interactions, and no additional identifiable private information or specimens are being obtained by the investigators under the  91探花IRB\u2019s oversight.<\/strong> This is true even if the  91探花study data have not yet been analyzed by the overall study statistical center\/personnel under the oversight of another IRB.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<h2 id=\"2\">Steps to Close Your IRB Approval<\/h2>\n<div class=\"accordion \" id=\"accordion\">\n<div class=\"screen-reader-text\"><\/div>\n<div class=\"card\">\n<div class=\"card-header\" id=\"accordion-header\">\n<h3 class=\"mb-0\"><button class=\"btn btn-link\" type=\"button\" data-toggle=\"collapse\" data-target=\"#collapse\" aria-expanded=\"false\" aria-controls=\"collapse\"><span class=\"btn-text\">Step 1: Complete the Status Report Form <\/span><span class=\"arrow-box\"><span class=\"arrow\"><\/span><\/span><\/button><\/h3>\n<\/div>\n<div id=\"collapse\" class=\"collapse \" aria-labelledby=\"collapse\" data-parent=\"#accordion\" role=\"region\">\n<p><b>To request study closure, complete the <a href=\"https:\/\/www.washington.edu\/research\/forms-and-templates\/application-status-report-renew-or-close\/\">Status Report form<\/a>.<\/b><\/p>\n<\/div>\n<\/div>\n<div class=\"card\">\n<div class=\"card-header\" id=\"accordion-header\">\n<h3 class=\"mb-0\"><button class=\"btn btn-link\" type=\"button\" data-toggle=\"collapse\" data-target=\"#collapse\" aria-expanded=\"false\" aria-controls=\"collapse\"><span class=\"btn-text\">Step 2: Prepare Any Supporting Documents for Upload (If Needed)<\/span><span class=\"arrow-box\"><span class=\"arrow\"><\/span><\/span><\/button><\/h3>\n<\/div>\n<div id=\"collapse\" class=\"collapse \" aria-labelledby=\"collapse\" data-parent=\"#accordion\" role=\"region\">\n<p><b>Most closure applications only require the status report form<\/b>, but you have the option to upload other documents related to the continuing review.<\/p>\n<p><b>Any DSMB reports should be submitted separately using the <a href=\"https:\/\/www.washington.edu\/research\/hsd\/study-activities\/report-events-and-new-information\/\">reporting process<\/a>.\u00a0<\/b><\/p>\n<\/div>\n<\/div>\n<div class=\"card\">\n<div class=\"card-header\" id=\"accordion-header\">\n<h3 class=\"mb-0\"><button class=\"btn btn-link\" type=\"button\" data-toggle=\"collapse\" data-target=\"#collapse\" aria-expanded=\"false\" aria-controls=\"collapse\"><span class=\"btn-text\">Step 3: Complete the Continuing Review in Zipline<\/span><span class=\"arrow-box\"><span class=\"arrow\"><\/span><\/span><\/button><\/h3>\n<\/div>\n<div id=\"collapse\" class=\"collapse \" aria-labelledby=\"collapse\" data-parent=\"#accordion\" role=\"region\">\n<ul>\n<li>Navigate to the study you need to renew and click Renew or Close under Next Steps<\/li>\n<\/ul>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-31128 size-full\" src=\"https:\/\/www.washington.edu\/research\/wp-content\/uploads\/2019\/12\/Continuing-Review-and-Closure-Homepage-Renew-or-Close.png\" alt=\"screenshot of the renew or close button for a zipline study\" width=\"729\" height=\"596\" srcset=\"https:\/\/www.washington.edu\/research\/wp-content\/uploads\/2019\/12\/Continuing-Review-and-Closure-Homepage-Renew-or-Close.png 729w, https:\/\/www.washington.edu\/research\/wp-content\/uploads\/2019\/12\/Continuing-Review-and-Closure-Homepage-Renew-or-Close-300x245.png 300w, https:\/\/www.washington.edu\/research\/wp-content\/uploads\/2019\/12\/Continuing-Review-and-Closure-Homepage-Renew-or-Close-375x307.png 375w\" sizes=\"auto, (max-width: 729px) 100vw, 729px\" \/><\/p>\n<ul>\n<li>Select Continuing Review as the purpose of the submission<\/li>\n<\/ul>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-53738 size-full\" src=\"https:\/\/www.washington.edu\/research\/wp-content\/uploads\/Closure-select-CR.png\" alt=\"screenshot of Zipline showing &quot;Continuing Review&quot; selected as the answer to &quot;What is the purpose of this submission&quot; on the Modification\/Continuing Review\/Study Closure page\" width=\"766\" height=\"278\" srcset=\"https:\/\/www.washington.edu\/research\/wp-content\/uploads\/Closure-select-CR.png 766w, https:\/\/www.washington.edu\/research\/wp-content\/uploads\/Closure-select-CR-300x109.png 300w, https:\/\/www.washington.edu\/research\/wp-content\/uploads\/Closure-select-CR-375x136.png 375w, https:\/\/www.washington.edu\/research\/wp-content\/uploads\/Closure-select-CR-750x272.png 750w\" sizes=\"auto, 100vw\" \/><\/p>\n<ul>\n<li>Complete the forms and upload the status report form and any supporting documents\n<ul>\n<li>If you indicate that the first 4 research milestones have been met, you will automatically be prompted to acknowledge that the study will be closed.<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-45422 size-full\" src=\"https:\/\/www.washington.edu\/research\/wp-content\/uploads\/2019\/12\/Continuing-Review-and-Closure-Homepage-Closure.png\" alt=\"screenshot of the top 4 research milestones checked\" width=\"624\" height=\"198\" \/><\/p>\n<p><strong>For step by step instructions:<\/strong><\/p>\n<ul>\n<li><a href=\"https:\/\/www.washington.edu\/research\/hsd\/training\/zipline-online-help-library\/continuing-review-and-closure\/\">Submit Continuing Review or Closure<\/a><\/li>\n<\/ul>\n<\/div>\n<\/div>\n<div class=\"card\">\n<div class=\"card-header\" id=\"accordion-header\">\n<h3 class=\"mb-0\"><button class=\"btn btn-link\" type=\"button\" data-toggle=\"collapse\" data-target=\"#collapse\" aria-expanded=\"false\" aria-controls=\"collapse\"><span class=\"btn-text\">Step 4: The PI or a PI Proxy must submit<\/span><span class=\"arrow-box\"><span class=\"arrow\"><\/span><\/span><\/button><\/h3>\n<\/div>\n<div id=\"collapse\" class=\"collapse \" aria-labelledby=\"collapse\" data-parent=\"#accordion\" role=\"region\">\n<p>The Submit activity must be <b>completed by the PI or a PI proxy<\/b> once the continuing review is ready to go to HSD.<\/p>\n<ul>\n<li>Select <b>Submit<\/b> in the continuing review workspace and provide required verifications<\/li>\n<\/ul>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-31129 size-full\" src=\"https:\/\/www.washington.edu\/research\/wp-content\/uploads\/Managing-Multi-site-Studies-submit-CR.png\" alt=\"Screenshot of the submit button for a continuing review\" width=\"252\" height=\"307\" \/><\/p>\n<p>&nbsp;<\/p>\n<\/div>\n<\/div>\n<\/div>\n<h2 id=\"3\">What To Expect After Submitting<\/h2>\n<p>The continuing review transitions to Pre-Review state and is now in HSD\u2019s queue for review.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-31126 size-large\" src=\"https:\/\/www.washington.edu\/research\/wp-content\/uploads\/Continuing-Review-and-Closure-CR-in-pre-review.png\" alt=\"screenshot of a continuing review in Pre-Review state\" width=\"1024\" height=\"337\" \/><\/p>\n<p>After the IRB has reviewed the application, the PI, any PI proxies, and primary contact will receive a notification that:<\/p>\n<ul>\n<li>The IRB has approved the closure; OR<\/li>\n<li>The IRB requires more information or a change before approving the closure<\/li>\n<\/ul>\n<p>Visit <a href=\"https:\/\/www.washington.edu\/research\/hsd\/training\/zipline-online-help-library\/respond-to-hsd\/\">Respond to HSD<\/a> for more information on submitting responses.<\/p>\n<p><b>After Closure<\/b><\/p>\n<p>After the continuing review is approved, the parent study will be updated. For closure requests, the parent study status changes to Closed. The PI, PI proxy, and primary contact also receive a notification containing the Closure letter.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Table of Contents Before You Begin Are you required to close your application? Does your study meet the criteria for closure? Common Concerns Steps to Close&#8230;<\/p>\n","protected":false},"author":15,"featured_media":0,"parent":11143,"menu_order":5,"comment_status":"closed","ping_status":"closed","template":"templates\/page-builder-units-small-hero.php","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-5777","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.1.1 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Close Your IRB Application -  91探花Research<\/title>\n<meta name=\"description\" content=\"Overview of how to close an approved study.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.washington.edu\/research\/hsd\/study-activities\/close\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Close Your IRB Application - 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